Article
Allelotype of non-small cell lung carcinoma--comparison between loss of heterozygosity in squamous cell carcinoma and adenocarcinoma.
Cancer research - 1 May 1992
Tsuchiya E, Nakamura Y, Weng S Y, Nakagawa K, Tsuchiya S, Sugano H, Kitagawa T
Abstract excerpt
We examined loss of heterozygosity (LOH) on all autosomal chromosomes in 53 non-small cell lung carcinomas. Frequent LOH was observed on the long arms of chromosomes 1 (37%), 2 (31%), 5 (30%), 8 (31%), and 13 (32%), and the short arms of chromosomes 3 (54%) and 17 (62%). LOH on chromosomes 3p and 17p was observed in all informative cases of squamous cell carcinoma, but was significantly less frequent in...
Topics
- Adenocarcinoma
- Alleles
- Blotting, Southern
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Heterozygote
- Humans
- Lung Neoplasms
