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Article

Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer

17 May 2005

Abstract excerpt

We extensively allelotyped a panel of 71 microdissected primary surgically resected non small cell lung cancer (NSCLC) tumors to identify chromosomal regions that are likely to contain tumor suppressor genes (TSGs) or associated with clinicopathologic and prognostic effects. Loss of heterozygosity (LOH) was detected by genotyping of 177 microsatellite markers and correlation of LOH with clinicopathologic...

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PMID: 15900585
DOI: 10.1002/ijc.21178

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