Targeted disruption of 01H1 encoding a particular H1 histone variant causes changes in protein patterns in the DT40 chicken B cell line.

doi:10.1006/jmbi.1995.0662

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Article

Targeted disruption of 01H1 encoding a particular H1 histone variant causes changes in protein patterns in the DT40 chicken B cell line.

Journal of molecular biology - 15 Dec 1995

Seguchi K, Takami Y, Nakayama T

Abstract excerpt

Six members of the chicken H1 gene family, all of which are located in two major histone gene clusters, have been shown to encode six different protein variants. The intracellular mRNA level from one of them, 01H1, encoding the 01H1 variant composed of 218 amino acid residues, constitutes 9.9% of...

Topics

Alleles
Animals
B-Lymphocytes
Cell Line
Chickens
Electrophoresis, Gel, Two-Dimensional
Gene Transfer Techniques
Heterozygote
Histones
Homozygote
Mutation
RNA, Messenger
Transcription, Genetic

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