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Article

The relationship between the sibling recurrence-risk ratio and genotype relative risk.

American journal of human genetics - 1 Feb 2000

Rybicki B A, Elston R C

Abstract excerpt

The recurrence-risk ratio of disease in siblings, lambdaS, is a standard parameter used in genetic analysis to estimate the statistical power for detection of a disease locus. However, the relationship between the underlying risk conferred by a disease-susceptibility allele and lambdaS has not been well described. The former is generally quantified as a genotype relative risk, gamma, and measures the ratio of...

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Identifiers

PMID: 10677319
DOI: 10.1086/302778
PMCID: PMC1288112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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