Article
Testing for association between disease and linked marker loci: a log-linear-model analysis.
American journal of human genetics - 1 May 1991
Tiret L, Amouyel P, Rakotovao R, Cambien F, Ducimetière P
Abstract excerpt
One approach frequently used for identifying genetic factors involved in the process of a complex disease is the comparison of patients and controls for a number of genetic markers near a candidate gene. The analysis of such association studies raises some specific problems because of the fact that genotypic and not gametic data are generally available. We present a log-linear-model analysis providing a valid...
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