Article
On the use of sibling recurrence risks to select environmental factors liable to interact with genetic risk factors.
European journal of human genetics : EJHG - 1 Jan 2010
Kazma Rémi, Bonaïti-Pellié Catherine, Norris Jill M, Génin Emmanuelle
Abstract excerpt
Gene-environment interactions are likely to be involved in the susceptibility to multifactorial diseases but are difficult to detect. Available methods usually concentrate on some particular genetic and environmental factors. In this paper, we propose a new method to determine whether a given exposure is susceptible to interact with unknown genetic factors. Rather than focusing on a specific genetic factor, the...
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