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Article

The Brucella abortus Lon functions as a generalized stress response protease and is required for wild-type virulence in BALB/c mice.

Molecular microbiology - 1 Feb 2000

Robertson G T, Kovach M E, Allen C A, Ficht T A, Roop R M

Abstract excerpt

The gene encoding a Lon protease homologue has been cloned from Brucella abortus. The putative Brucella abortus Lon shares > 60% amino acid identity with its Escherichia coli counterpart and the recombinant form of this protein restores the capacity of an Escherichia coli lon mutant to resist killing by ultraviolet irradiation and regulate the expression of a cpsB:lacZ fusion to wild-type levels. A sigma32 type...

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Identifiers

PMID: 10672180
DOI: 10.1046/j.1365-2958.2000.01726.x

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The Brucella abortus Lon functions as a generalized stress response protease and is required for wild-type virulence in BALB/c mice.PMID 10672180Read ↗

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