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Article

The Lon-1 Protease Is Required by Borrelia burgdorferi To Infect the Mammalian Host.

Infection and immunity - 20 May 2020

Thompson Christina, Mason Charlotte, Parrilla Shidoya, Ouyang Zhiming

Abstract excerpt

Borrelia burgdorferi encodes a functional homolog of canonical Lon protease termed Lon-2. In addition, B. burgdorferi encodes a second Lon homolog called Lon-1. Recent studies suggest that Lon-1 may function differently from the prototypical Lon protease. However, the function of Lon-1 in B. burgdorferi biology remains virtually unknown. Particularly, the contribution of Lon-1 to B. burgdorferi fitness and...

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Identifiers

PMID: 32205400
DOI: 10.1128/IAI.00951-19
PMCID: PMC7240077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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