Article
Early transcriptional responses of internalization defective Brucella abortus mutants in professional phagocytes, RAW 264.7.
BMC genomics - 27 Jun 2013
Cha Seung Bin, Lee Won Jung, Shin Min Kyoung, Jung Myung Hwan, Shin Seung Won, Yoo An Na, Kim Jong Wan, Yoo Han Sang
Abstract excerpt
BACKGROUND: Brucella abortus is an intracellular zoonotic pathogen which causes undulant fever, endocarditis, arthritis and osteomyelitis in human and abortion and infertility in cattle. This bacterium is able to invade and replicate in host macrophage instead of getting removed by this defense mechanism. Therefore, understanding the interaction between virulence of the bacteria and the host cell is important to...
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