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Article

A conserved domain in Escherichia coli Lon protease is involved in substrate discriminator activity.

Journal of bacteriology - 1 Apr 1999

Ebel W, Skinner M M, Dierksen K P, Scott J M, Trempy J E

Abstract excerpt

Lon protease of Escherichia coli regulates a diverse set of physiological responses including cell division, capsule production, plasmid stability, and phage replication. Little is known about the mechanism of substrate recognition by Lon. To examine the interaction of Lon with two of its substrates, RcsA and SulA, we generated point mutations in lon which affected its substrate specificity. The most informative...

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Identifiers

PMID: 10094703
DOI: 10.1128/JB.181.7.2236-2243.1999
PMCID: PMC93638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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