Article
Mice lacking the cell adhesion molecule Thy-1 fail to use socially transmitted cues to direct their choice of food.
Current biology : CB - 27 Jan 2000
Mayeux-Portas V, File S E, Stewart C L, Morris R J
Abstract excerpt
BACKGROUND: Thy-1 is a major cell-surface glycoprotein of mature neurons and certain other cells, including those of the lymphoreticular system. Despite being the simplest member of the immunoglobulin superfamily, the biological role of Thy-1 has proved elusive. Analysis of Thy-1 null mice has shown the presence of excessive GABAergic inhibition of neurotransmission in the dentate gyrus of the hippocampal...
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