Increased anxiety of mice lacking the serotonin1A receptor.

doi:10.1073/pnas.95.18.10734

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Article

Increased anxiety of mice lacking the serotonin1A receptor.

Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1998

Parks C L, Robinson P S, Sibille E, Shenk T, Toth M

Abstract excerpt

Brain serotonin (5-HT) has been implicated in a number of physiological processes and pathological conditions. These effects are mediated by at least 14 different 5-HT receptors. We have inactivated the gene encoding the 5-HT1A receptor in mice and found that receptor-deficient animals have an in...

Topics

Animals
Anxiety
Base Sequence
Behavior, Animal
Brain
DNA Primers
Female
Genotype
Male
Mice
Mice, Inbred BALB C
Mice, Knockout
Receptors, Serotonin
Receptors, Serotonin, 5-HT1

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