Article
Cognition in transmembrane domain neuregulin 1 mutant mice.
Neuroscience - 27 Oct 2010
Duffy L, Cappas E, Lai D, Boucher A A, Karl T
Abstract excerpt
Neuregulin 1 (NRG1), which has been implicated in the development of schizophrenia, is expressed widely throughout the brain and influences key neurodevelopmental processes such as myelination and neuronal migration. The heterozygous transmembrane domain Nrg1 mutant mouse (Nrg1 TM HET) exhibits a neurobehavioural phenotype relevant for schizophrenia research, characterized by the development of locomotor...
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