Article
LRRTM1-deficient mice show a rare phenotype of avoiding small enclosures--a tentative mouse model for claustrophobia-like behaviour.
Behavioural brain research - 1 Feb 2013
Voikar V, Kulesskaya N, Laakso T, Lauren J, Strittmatter S M, Airaksinen M S
Abstract excerpt
The LRRTM family proteins have been shown to act as synaptogenic cell adhesion molecules via interaction with presynaptic neurexins and are associated with neuropsychiatric disorders. LRRTM1-knockout mice have subtle morphological deficits in excitatory hippocampal synapses and were suggested to...
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