Article
Endocannabinoids render exploratory behaviour largely independent of the test aversiveness: role of glutamatergic transmission.
Genes, brain, and behavior - 1 Oct 2009
Jacob W, Yassouridis A, Marsicano G, Monory K, Lutz B, Wotjak C T
Abstract excerpt
To investigate the impact of averseness, controllability and familiarity of a test situation on the involvement of the endocannabinoid system in the regulation of exploratory behaviour, we tested conventional and conditional cannabinoid receptor type 1 (CB1)-deficient mice in behavioural paradigms with different emotional load, which depended on the strength of illumination and the ability of the animals to avoid...
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