Article
Expression analysis of the group IIA secretory phospholipase A(2) in mice with differential susceptibility to azoxymethane-induced colon tumorigenesis.
Carcinogenesis - 1 Feb 2000
Papanikolaou A, Wang Q S, Mulherkar R, Bolt A, Rosenberg D W
Abstract excerpt
The murine non-pancreatic secretory phospholipase A(2) (sPLA(2)) has been proposed as a tumor modifier of multiple intestinal neoplasia (Min). A genetic polymorphism in the mouse gene that causes a disruption in exon 3 results in loss of functional protein. Mouse strains with a disrupted sPLA(2)...
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