Article
The roles of sPLA2-IIA (Pla2g2a) in cancer of the small and large intestine.
Frontiers in bioscience : a journal and virtual library - 1 May 2008
Fijneman Remond J A, Cormier Robert T
Abstract excerpt
The mouse secretory phospholipase A2 group IIA (sPLA2-IIA) gene Pla2g2a has been identified as a susceptibility gene for cancer of the small and large intestine. Interestingly, unlike most previously identified tumor susceptibility genes, Pla2g2a does not behave like a classical oncogene or tumor suppressor gene. Hence, identification of its biological functions in tumor development may shed new light on general...
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