Article
Association of KM genotype with bullous pemphigoid.
Journal of autoimmunity - 1 Feb 2000
Raux G, Gilbert D, Joly P, Daveau M, Martel P, Christ M, Tron F
Abstract excerpt
Association of kappa light chain immunoglobulin allotypes with bullous pemphigoid was examined in 101 Caucasian patients. Km alleles were determined by polymerase chain reaction amplification followed by restriction enzyme digestion. The frequency of Km(3)/Km(1,2)kappa light-chain genotype was found to be significantly associated with the disease, while that of the Km(3)homozygous genotype was significantly...
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