Article
Systemic lupus erythematosus is not associated with allotypic markers of immunoglobulin kappa in Caucasians.
The Journal of rheumatology - 1 May 1994
Singh R, Mullinax P F, Moxley G
Abstract excerpt
OBJECTIVE: To determine whether systemic lupus erythematosus (SLE) is associated with a specific Km genotype or allele. Specific genetic markers located both within the major histocompatibility complex (MHC) and outside the MHC have been associated with SLE. However, serologic studies of Km allotypes have led to contradictory results. METHODS: A novel molecular genetic technique was used to determine Km...
Topics
- Adult
- Female
- Genetic Markers
- Genotype
- Humans
- Immunoglobulin Allotypes
- Immunoglobulin kappa-Chains
- Lupus Erythematosus, Systemic
- Male
- Middle Aged
- Polymerase Chain Reaction
