Article
Immunoglobulin GM and KM allotypes in systemic lupus erythematosus.
Experimental and clinical immunogenetics - 1 Jan 2001
Pandey J P, Cooper G S, Treadwell E L, Gilkeson G S, St Clair E W, Dooley M A
Abstract excerpt
Genetic variation in immunoglobulin gamma (GM) and kappa (KM) chains was associated with systemic lupus erythematosus (SLE) in some studies. However, the data are conflicting, and only one study examined associations in African-Americans. We examined GM and KM allotypes, by race, in a population-based case-control study of SLE. Sera from patients (n = 222) and controls (n = 273) were typed for GM and KM allotypes...
Topics
- Adolescent
- Adult
- Black People
- Female
- Humans
- Immunogenetics
- Immunoglobulin Allotypes
- Immunoglobulin Gm Allotypes
- Lupus Erythematosus, Systemic
- Male
- Phenotype