Article
Immunoglobulin GM and KM genotypes in Korean patients with systemic lupus erythematosus.
Rheumatology international - 1 Jan 2007
Lee E B, Lee Y J, Shin D H, Choi Y M, Park M H, Pandey J P, Song Y W
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune complex deposition. We genotyped immunoglobulin allotypes of G1M (f,z), G2M (n+,n-), G3M (b,g) and KM (1,3) in 142 Korean patients with SLE and 200 healthy controls to investigate the role of the allotypes in SLE. The allele frequency of G1M (z) was significantly higher in patients with SLE as compared to the healthy controls...
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