Pemphigus is not associated with allotypic markers of immunoglobulin kappa.

doi:10.1038/sj.gene.6363817

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Article

Pemphigus is not associated with allotypic markers of immunoglobulin kappa.

Genes and immunity - 1 Feb 2002

Zitouni M, Martel P, Ben Ayed M, Raux G, Gilbert D, Joly P, Mokhtar I, Ridha Kamoun M, Turki H, Zahaf A, Mokni M, Ben Osman A, Masmoudi H, Makni S, Tron F

Abstract excerpt

The kappa light chain constant region of immunoglobulins bears polymorphic markers involved in susceptibility to various autoimmune diseases. To determine whether it also contributes to the occurrence of pemphigus, a group of autoimmune blistering skin diseases owing to pathogenic autoantibodies, the genotypic frequencies of Km allotypes were evaluated in patients with pemphigus foliaceus or pemphigus vulgaris...

Topics

Adult
Aged
Autoantibodies
Female
France
Gene Frequency
Genotype
Humans
Immunoglobulin Allotypes
Immunoglobulin kappa-Chains
Male
Middle Aged
Pemphigus
Polymorphism, Genetic

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Identifiers

PMID: 11857063
DOI: 10.1038/sj.gene.6363817

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