Article
Association of Km3 allotype with increased serum levels of autoantibodies against muscle acetylcholine receptor in myasthenia gravis.
Journal of neuroimmunology - 1 May 1994
Dondi E, Gajdos P, Bach J F, Garchon H J
Abstract excerpt
Association of immunoglobulin allotypes with myasthenia gravis was examined in a set of 84 patients presenting autoantibodies against muscle acetylcholine receptor (AChR). Km and G1m(f)/G1m(z) allotypes were determined by PCR-amplification followed by hybridization with allele-specific oligonucle...
Topics
- Alleles
- Autoantibodies
- Humans
- Immunoglobulin Allotypes
- Immunoglobulin Gm Allotypes
- Immunoglobulin kappa-Chains
- Muscles
- Myasthenia Gravis
- Polymerase Chain Reaction
- Receptors, Cholinergic
