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Article

Embryonic inheritance of the chromatin organisation of the imprinted H19 domain in mouse spermatozoa.

Mechanisms of development - 1 Feb 2000

Banerjee S, Singh P B, Rasberry C, Cattanach B M

Abstract excerpt

Insulin-like growth factor 2 (Igf 2) and H19 genes are oppositely imprinted and as such have been most extensively studied imprinted genes both genetically and at the molecular level. Imprints of the H19 gene, being established during spermatogenesis, are epigenetically transmitted to the somatic cells of the embryo. Current hypotheses attempting to explain the allele-specific silence of the H19 gene include DNA...

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Source

Identifiers

PMID: 10640705
DOI: 10.1016/s0925-4773(99)00254-3

Genes

DMD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Embryonic inheritance of the chromatin organisation of the imprinted H19 domain in mouse spermatozoa.PMID 10640705Read ↗

Parental allele-specific chromatin configuration in a boundary-imprinting-control element upstream of the mouse H19 gene.Semantic proximity Read ↗

Establishment and maintenance of H19 imprinting in the germline and preimplantation embryo.Semantic proximity Read ↗

Developmental profile of H19 differentially methylated domain (DMD) deletion alleles reveals multiple roles of the DMD in regulating allelic expression and DNA methylation at the imprinted H19/Igf2 locus.Semantic proximity Read ↗

A paternal-specific methylation imprint marks the alleles of the mouse H19 gene.Semantic proximity Read ↗

Imprinted expression and methylation of the mouse H19 gene are conserved in extraembryonic lineages.Semantic proximity Read ↗

The 5' flank of mouse H19 in an unusual chromatin conformation unidirectionally blocks enhancer-promoter communication.Semantic proximity Read ↗

Dynamic readjustment of parental methylation patterns of the 5'-flank of the mouse H19 gene during in vitro organogenesis.Semantic proximity Read ↗

Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locus.Semantic proximity Read ↗

Mechanisms of Igf2/H19 Imprinting: DNA Methylation, Chromatin and Long-Distance Gene RegulationSemantic proximity Read ↗

Analysis of sequence upstream of the endogenous H19 gene reveals elements both essential and dispensable for imprinting.Semantic proximity Read ↗

Acquisition of the H19 methylation imprint occurs differentially on the parental alleles during spermatogenesis.Semantic proximity Read ↗

A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development.Semantic proximity Read ↗

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