Article
Identification of quantitative trait loci for serum cholesterol levels in stroke-prone spontaneously hypertensive rats.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2000
Kato N, Tamada T, Nabika T, Ueno K, Gotoda T, Matsumoto C, Mashimo T, Sawamura M, Ikeda K, Nara Y, Yamori Y
Abstract excerpt
The stroke-prone spontaneously hypertensive rat (SHRSP) has been reported to show significantly lower levels of serum total cholesterol than the normotensive control strain Wistar-Kyoto rat (WKY). Because selective inbreeding was conducted for stroke proneness, this concomitantly inherited characteristic of SHRSP may play some pathophysiological role in stroke. We evaluated the genetic determinants of the...
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