Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats.

BMC cardiovascular disorders - 3 Jun 2003

Yu Hongwei, Pandit Bhaswati, Klett Eric, Lee Mi-Hye, Lu Kangmo, Helou Khalil, Ikeda Ikuo, Egashira Nami, Sato Masao, Klein Richard, Batta Ashok, Salen Gerald, Patel Shailendra B

Abstract excerpt

BACKGROUND: Elevated plant sterol accumulation has been reported in the spontaneously hypertensive rat (SHR), the stroke-prone spontaneously hypertensive rat (SHRSP) and the Wistar-Kyoto (WKY) rat. Additionally, a blood pressure quantitative trait locus (QTL) has been mapped to rat chromosome 6 in a New Zealand genetically hypertensive rat strain (GH rat). ABCG5 and ABCG8 (encoding sterolin-1 and sterolin-2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to In Situ Hybridization, Fluorescence
Share to Lipoproteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation, Missense

Share to Phytosterols

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Share to Rats, Sprague-Dawley

Share to Rats, Wistar

Source

Open in PubMed Open full text

Identifiers

PMID: 12783625
DOI: 10.1186/1471-2261-3-4
PMCID: PMC165443

Genes

ABCG5
ABCG8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats.PMID 12783625Read ↗

Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively.Semantic proximity Read ↗

A detailed Hapmap of the Sitosterolemia locus spanning 69 kb; differences between Caucasians and African-Americans.Semantic proximity Read ↗

Recent advances in understanding the STSL locus and ABCG5/ABCG8 biology.Semantic proximity Read ↗

Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption.Semantic proximity Read ↗

Genetic basis of sitosterolemia.Semantic proximity Read ↗

Sitosterolaemia: pathophysiology, clinical presentation and laboratory diagnosisSemantic proximity Read ↗

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance.Semantic proximity Read ↗

Thematic Review Series: Lipid Transfer Proteins ABCG5 and ABCG8: more than a defense against xenosterolsSemantic proximity Read ↗

Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8.Semantic proximity Read ↗

Clinical and Genetic Analysis of a Family With Sitosterolemia Caused by a Novel ATP-Binding Cassette Subfamily G Member 5 Compound Heterozygous MutationSemantic proximity Read ↗

Sitosterolemia, Hypercholesterolemia, and Coronary Artery Disease.Semantic proximity Read ↗

Compound heterozygous mutations in ABCG5 or ABCG8 causing Chinese familial Sitosterolemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.