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Article

Genome-wide search for QTLs for apolipoprotein A-I level in elderly Swedish DZ twins: evidence of female-specific locus on 15q11-13.

European journal of human genetics : EJHG - 1 Sept 2008

Magnusson Patrik K E, Boman Marcus, de Faire Ulf, Perola Markus, Peltonen Leena, Pedersen Nancy L

Abstract excerpt

The effect of genetic variants underlying atherosclerosis is thought to be mediated through intermediate phenotypes such as serum cholesterol levels. Localization of quantitative trait loci influencing levels of serum lipids and (apo)lipoproteins may aid in the search for determinants of susceptibility to atherosclerotic diseases. Since apolipoprotein A-I is the primary protein constituent of high-density...

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PMID: 18322452
DOI: 10.1038/ejhg.2008.50

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