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Article

Genetic analysis of transcription-associated mutation in Saccharomyces cerevisiae.

Genetics - 1 Jan 2000

Morey N J, Greene C N, Jinks-Robertson S

Abstract excerpt

High levels of transcription are associated with elevated mutation rates in yeast, a phenomenon referred to as transcription-associated mutation (TAM). The transcription-associated increase in mutation rates was previously shown to be partially dependent on the Rev3p translesion bypass pathway, thus implicating DNA damage in TAM. In this study, we use reversion of a pGAL-driven lys2DeltaBgl allele to further...

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Identifiers

PMID: 10628973
DOI: 10.1093/genetics/154.1.109
PMCID: PMC1460922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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