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Article

Association of increased spontaneous mutation rates with high levels of transcription in yeast.

Science (New York, N.Y.) - 16 Jun 1995

Datta A, Jinks-Robertson S

Abstract excerpt

Complex processes such as transcription, replication, repair, and recombination require changes in chromatin structure and the interactions of numerous trans-acting factors with DNA sequences, raising the possibility that these processes may be interrelated. Here the effect of transcription on the rate of spontaneous mutation in the yeast Saccharomyces cerevisiae was examined. With the use of a lys2 frameshift...

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Source

Identifiers

PMID: 7777859
DOI: 10.1126/science.7777859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of increased spontaneous mutation rates with high levels of transcription in yeast.PMID 7777859Read ↗

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