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Article

Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 2000

Barreto V, Cumano A

Abstract excerpt

Ig H chain (IgH) allelic exclusion remains a puzzling topic. Here, we address the following question: Do phenotypic IgH allelically included cells exist in normal mice and, if so, at what frequency? Sorted cells from heterozygous mice were evaluated for the expression of both IgM allotypes by double intracytoplasmic stainings. Dual expressors were found at a frequency of 1 in 104 splenic B cells. These data were...

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Source

Identifiers

PMID: 10623837
DOI: 10.4049/jimmunol.164.2.893

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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