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scRNA-seq revealed the special IG H&L V(D)J allelic inclusion rearrangement and the high proportion dual BCR expressing B cells

2023-04-18

Abstract excerpt

<h4>abstract</h4> Since the first report of V (D) J “ allelic exclusion/inclusion”and” dual BCR “in 1961, despite continuous new discoveries, the proportion and source mechanism of dual BCR under physiological conditions have been puzzling immuologists.This study takes advantage of the single cell V (D) J sequencing technology, which can perfectly match the heavy and light chains of BCR at the level of a single B...

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Literature Corpus work
870aa43e-40e5-53bf-b9b5-086acef4bef9
DOI
10.1101/2023.04.13.23288510
Open publication

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scRNA-seq revealed the special IG H&L V(D)J allelic inclusion rearrangement and the high proportion dual BCR expressing B cellsDOI 10.1101/2023.04.13.23288510
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