Article
Evidence for the genetic role of human leukocyte antigens in low frequency DRB1*1501 multiple sclerosis patients in Israel.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Dec 1999
Karni A, Kohn Y, Safirman C, Abramsky O, Barcellos L, Oksenberg J R, Kahana E, Karussis D, Chapman J, Brautbar C
Abstract excerpt
A strong association exists between multiple sclerosis (MS) and the DRB1*1501 haplotype, in most populations. Linkage of Multiple Sclerosis (MS) with the MHC or HLA region on chromosome 6p21 has previously been observed in DRB1*1501 positive MS families. A group of 13 Israeli multiplex MS familie...
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