Article
Mediterranean and Amerindian MHC class II alleles are associated with multiple sclerosis in Mexicans.
Acta neurologica Scandinavica - 1 Nov 2005
Aláez C, Corona T, Ruano L, Flores H, Loyola M, Gorodezky C
Abstract excerpt
OBJECTIVES: Human leukocyte antigen (HLA)-DRB1, DQA1, DQB1 allele typing was performed in Mexicans Mestizos with multiple sclerosis (MS) to define the HLA class II alleles associated with the disease in this population. METHODS: Patients (n = 51) diagnosed according to the Poser criteria and a group of 173 unrelated healthy subjects were studied. PCR-SSOP and PCR-SSP were used for genotyping. RESULTS: Fifty five...
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