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Article

Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations.

PloS one - 1 Jan 2012

Alcina Antonio, Abad-Grau María Del Mar, Fedetz María, Izquierdo Guillermo, Lucas Miguel, Fernández Oscar, Ndagire Dorothy, Catalá-Rabasa Antonio, Ruiz Agustín, Gayán Javier, Delgado Concepción, Arnal Carmen, Matesanz Fuencisla

Abstract excerpt

The human leukocyte antigen (HLA) DRB1*1501 has been consistently associated with multiple sclerosis (MS) in nearly all populations tested. This points to a specific antigen presentation as the pathogenic mechanism though this does not fully explain the disease association. The identification of expression quantitative trait loci (eQTL) for genes in the HLA locus poses the question of the role of gene expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22253788
DOI: 10.1371/journal.pone.0029819
PMCID: PMC3258250

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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