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Article

Isolation and characterization of Francisella novicida mutants defective in lipopolysaccharide biosynthesis.

FEMS microbiology letters - 1 Jan 2000

Cowley S C, Gray C J, Nano F E

Abstract excerpt

In order to identify genes involved in LPS biosynthesis we isolated random mutants generated by transposon insertion in Francisella novicida. The resulting mutant bank yielded mutants with three distinct LPS phenotypes, and three representative mutants were chosen for further study. One mutant that had short O-antigen chains was sensitive to serum; this mutant and one other were more sensitive to killing by...

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PMID: 10612732
DOI: 10.1111/j.1574-6968.2000.tb08874.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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