Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MglA and MglB are required for the intramacrophage growth of Francisella novicida.

Molecular microbiology - 1 Jul 1998

Baron G S, Nano F E

Abstract excerpt

Francisella novicida is a facultative intracellular pathogen capable of growing in macrophages. A spontaneous mutant of F. novicida defective for growth in macrophages was isolated on LB media containing the chromogenic phosphatase substrate 5-bromo-4-chloro-3-indolyl phosphate (X-p) and designated GB2. Using an in cis complementation strategy, four strains were isolated that are restored for growth in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line

Share to Cloning, Molecular

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 9701818
DOI: 10.1046/j.1365-2958.1998.00926.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MglA and MglB are required for the intramacrophage growth of Francisella novicida.PMID 9701818Read ↗

The Francisella pathogenicity island.Semantic proximity Read ↗

Identification of MglA-regulated genes reveals novel virulence factors in Francisella tularensis.Semantic proximity Read ↗

MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival.Semantic proximity Read ↗

Isolation and characterization of Francisella novicida mutants defective in lipopolysaccharide biosynthesis.Semantic proximity Read ↗

Molecular bases of proliferation of Francisella tularensis in arthropod vectorsSemantic proximity Read ↗

Mutations of Francisella novicida that alter the mechanism of its phagocytosis by murine macrophages.Semantic proximity Read ↗

The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm.Semantic proximity Read ↗

Burkholderia pseudomallei transcriptional adaptation in macrophagesSemantic proximity Read ↗

Pullulanase Is Necessary for the Efficient Intracellular Growth of Francisella tularensis.Semantic proximity Read ↗

Characterization of the pathogenicity island protein PdpA and its role in the virulence of Francisella novicida.Semantic proximity Read ↗

Disruption of Francisella tularensis Schu S4 iglI, iglJ, and pdpC genes results in attenuation for growth in human macrophages and in vivo virulence in mice and reveals a unique phenotype for pdpC.Semantic proximity Read ↗

RelA regulates virulence and intracellular survival of Francisella novicida.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.