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Article

Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages.

Infection and immunity - 1 Feb 2011

Lindemann Stephen R, Peng Kaitian, Long Matthew E, Hunt Jason R, Apicella Michael A, Monack Denise M, Allen Lee-Ann H, Jones Bradley D

Abstract excerpt

Francisella tularensis is capable of rampant intracellular growth and causes a potentially fatal disease in humans. Whereas many mutational studies have been performed with avirulent strains of Francisella, relatively little has been done with strains that cause human disease. We generated a near-saturating transposon library in the virulent strain Schu S4, which was subjected to high-throughput screening by...

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Identifiers

PMID: 21078861
DOI: 10.1128/IAI.00863-10
PMCID: PMC3028865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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