Article
A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogate.
Proceedings of the National Academy of Sciences of the United States of America - 16 Jan 2007
Gallagher Larry A, Ramage Elizabeth, Jacobs Michael A, Kaul Rajinder, Brittnacher Mitchell, Manoil Colin
Abstract excerpt
Francisella tularensis, the causative agent of tularemia, is one of the most infectious bacterial pathogens known and is a category A select agent. We created a sequence-defined, near-saturation transposon mutant library of F. tularensis novicida, a subspecies that causes a tularemia-like disease in rodents. The library consists of 16,508 unique insertions, an average of >9 insertions per gene, which is a...
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