Article
Uncovering the components of the Francisella tularensis virulence stealth strategy.
Frontiers in cellular and infection microbiology - 1 Jan 2014
Jones Bradley D, Faron Matthew, Rasmussen Jed A, Fletcher Joshua R
Abstract excerpt
Over the last decade, studies on the virulence of the highly pathogenic intracellular bacterial pathogen Francisella tularensis have increased dramatically. The organism produces an inert LPS, a capsule, escapes the phagosome to grow in the cytosol (FPI genes mediate phagosomal escape) of a variety of host cell types that include epithelial, endothelial, dendritic, macrophage, and neutrophil. This review focuses...
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