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Article

Mutations of Francisella novicida that alter the mechanism of its phagocytosis by murine macrophages.

PloS one - 29 Jul 2010

Lai Xin-He, Shirley Renee L, Crosa Lidia, Kanistanon Duangjit, Tempel Rebecca, Ernst Robert K, Gallagher Larry A, Manoil Colin, Heffron Fred

Abstract excerpt

Infection with the bacterial pathogen Francisella tularensis tularensis (F. tularensis) causes tularemia, a serious and debilitating disease. Francisella tularensis novicida strain U112 (abbreviated F. novicida), which is closely related to F. tularensis, is pathogenic for mice but not for man, making it an ideal model system for tularemia. Intracellular pathogens like Francisella inhibit the innate immune...

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Identifiers

PMID: 20686600
DOI: 10.1371/journal.pone.0011857
PMCID: PMC2912274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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