Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic regulation of single-stranded telomeres in Saccharomyces cerevisiae.

Genetics - 1 Feb 2008

Smith Stephanie, Banerjee Soma, Rilo Regina, Myung Kyungjae

Abstract excerpt

The temperature-sensitive phenotypes of yku70Delta and yku80Delta have provided a useful tool for understanding telomere homeostasis. Mutating the helicase domain of the telomerase inhibitor Pif1 resulted in the inactivation of cell cycle checkpoints and the subsequent rescue of temperature sensi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Fungal
Share to DNA, Fungal
Share to DNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Single-Stranded

Share to Gene Expression Regulation, Fungal

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 18245359
DOI: 10.1534/genetics.107.081091
PMCID: PMC2248362

Genes

BLM
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18245359-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic regulation of single-stranded telomeres in Saccharomyces cerevisiae.PMID 18245359Read ↗

not-yet-known not-yet-known not-yet-known unknown Short mre11Δ telomeres of Saccharomyces cerevisiae do not shorten further under thermal stress, in contrast to long pif1Δ telomeres: a few aspects of implicationsSemantic proximity Read ↗

Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.Semantic proximity Read ↗

Sgs1 RecQ helicase inhibits survival of Saccharomyces cerevisiae cells lacking telomerase and homologous recombination.Semantic proximity Read ↗

Mutations in the RAD27 and SGS1 genes differentially affect the chronological and replicative lifespan of yeast cells growing on glucose and glycerol.Semantic proximity Read ↗

Telomere-driven mutational processes in yeast.Semantic proximity Read ↗

Telomerase, the recombination machinery and Rap1 play redundant roles in yeast telomere protection.Semantic proximity Read ↗

Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku.Semantic proximity Read ↗

Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant.Semantic proximity Read ↗

C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae.Semantic proximity Read ↗

Pif1p helicase, a catalytic inhibitor of telomerase in yeast.Semantic proximity Read ↗

Mrc1, a non-essential DNA replication protein, is required for telomere end protection following loss of capping by Cdc13, Yku or telomerase.Semantic proximity Read ↗

A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.