Article
Kinase-independent functions of TEL1 in telomere maintenance.
Molecular and cellular biology - 1 Sept 2009
Ma Yunmei, Greider Carol W
Abstract excerpt
TEL1 is important in Saccharomyces cerevisiae telomere maintenance, and its kinase activity is required. Tel1p associates with telomeres in vivo, is enriched at short telomeres, and enhances the binding of telomerase components to short telomeres. However, it is unclear how the kinase activity and telomere association contribute to Tel1p's overall function in telomere length maintenance. To investigate this...
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