Article
Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast.
PLoS genetics - 1 Sept 2009
Liti Gianni, Haricharan Svasti, Cubillos Francisco A, Tierney Anna L, Sharp Sarah, Bertuch Alison A, Parts Leopold, Bailes Elizabeth, Louis Edward J
Abstract excerpt
In yeast, as in humans, telomere length varies among individuals and is controlled by multiple loci. In a quest to define the extent of variation in telomere length, we screened 112 wild-type Saccharomyces sensu stricto isolates. We found extensive telomere length variation in S. paradoxus isolates. This phenotype correlated with their geographic origin: European strains were observed to have extremely short...
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