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Article

Polymorphisms of the xenobiotic-metabolizing enzymes CYP1A1 and NAT-2 in systemic sclerosis and lupus erythematosus.

Advances in experimental medicine and biology - 1 Jan 1999

von Schmiedeberg S, Fritsche E, Rönnau A C, Specker C, Golka K, Richter-Hintz D, Schuppe H C, Lehmann P, Ruzicka T, Esser C, Abel J, Gleichmann E

Abstract excerpt

The etiology of systemic autoimmune diseases, such as systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) is still unknown. In several cases, however, xenobiotics (i.e. drugs and occupational agents) were identified as etiologic agents and associations with certain polymorphic alleles of xenobiotic-metabolizing enzymes have been reported. Cytochrome P4501A1 (CYP1A1) and N-acetyltransferase 2 (NAT-2)...

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PMID: 10599336
DOI: 10.1007/978-1-4615-4857-7_21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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