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Article

Influence of polymorphic N-acetyltransferases on non-malignant spontaneous disorders and on response to drugs.

Current drug metabolism - 1 Jul 2008

Ladero J M

Abstract excerpt

Polymorphic N-acetyl transferases (NAT) 1 and 2 are involved in detoxification of xenobiotic arylamines and hydralazines. These common environmental chemicals may be related to the pathogenesis of many spontaneous disorders, mainly malignancies, but also disimmune or degenerative diseases, for which a polygenic predisposition has been suggested. Hence, polymorphic NAT genes (NAT2 has been the most studied one)...

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Source

Identifiers

PMID: 18680473
DOI: 10.2174/138920008784892038

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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