Article
Lack of association between arylamine N-acetyltransferase 2 (NAT2) polymorphism and systemic sclerosis.
European journal of clinical pharmacology - 1 Jan 2005
Skretkowicz K, Skretkowicz J, Gawrońska-Szklarz B, Górnik W, Rychlik-Sych M, Sysa-Jedrzejowska A
Abstract excerpt
OBJECTIVES: It has been shown that exposure to some environmental toxins may induce scleroderma-like illness in predisposed individuals, but the etiopathogenesis of the idiopathic form of systemic sclerosis (SSc) remains obscure. The genetic background of this illness has been confirmed in multiple studies. We investigated whether patients with SSc differ from healthy subjects with regard to the enzymatic...
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