Article
Polymorphisms in NAT2 (N-acetyltransferase 2) gene in patients with systemic lupus erythematosus.
Revista brasileira de reumatologia - 1 Jan 2000
Santos Elaine Cristina Lima Dos, Pinto Amanda Chaves, Klumb Evandro Mendes, Macedo Jacyara Maria Brito
Abstract excerpt
OBJECTIVE: To investigate potential associations of four substitutions in NAT2 gene and of acetylator phenotype of NAT2 with systemic lupus erythematosus (SLE) and clinical phenotypes. METHODS: Molecular analysis of 481C>T, 590G>A, 857G>A, and 191G>A substitutions in the NAT2 gene was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique, from DNA extracted from...
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