Article
Acetylation genotype and phenotype in patients with systemic lupus erythematosus.
Pharmacological reports : PR - 1 Jan 2000
Rychlik-Sych Mariola, Skretkowicz Jadwiga, Gawrońska-Szklarz Barbara, Górnik Wanda, Sysa-Jedrzejowska Anna, Skretkowicz-Szarmach Kamila
Abstract excerpt
UNLABELLED: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting various tissues and organs. In the studies on SLE etiopathogenesis, a potential role of genetically determined impairment of xenobiotic metabolism has been emphasized. N-acetyltransferase 2 enzyme (NAT2) exhibits gene polymorphism and the acetylation rate with NAT2 involvement varies from person to person. The study on...
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