Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A long-range pseudoknot in Qbeta RNA is essential for replication.

Journal of molecular biology - 10 Dec 1999

Klovins J, van Duin J

Abstract excerpt

A puzzling aspect of replication of bacteriophage Qbeta RNA has always been that replicase binds at an internal segment, the M-site, some 1450 nt away from the 3' end. Here, we report on the existence of a long-range pseudoknot, base-pairing eight nt in the loop of the 3' terminal hairpin to a single-stranded interdomain sequence located about 1200 nt upstream, close to the internal replicase binding site....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coliphages
Share to Nucleic Acid Conformation
Share to RNA, Antisense

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to RNA Stability

Share to RNA, Viral

Share to RNA Viruses

Share to Thermodynamics

Share to Virus Replication

Source

Identifiers

PMID: 10588893
DOI: 10.1006/jmbi.1999.3274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A long-range pseudoknot in Qbeta RNA is essential for replication.PMID 10588893Read ↗

A Phylogenetically Conserved Hairpin-Type 3′ Untranslated Region Pseudoknot Functions in Coronavirus RNA ReplicationSemantic proximity Read ↗

Replication of alphaviruses requires a pseudoknot that involves the polyA tailSemantic proximity Read ↗

Altered 3'-terminal RNA structure in phage Qbeta adapted to host factor-less Escherichia coli.Semantic proximity Read ↗

Local structural and environmental factors define the efficiency of an RNA pseudoknot involved in programmed ribosomal frameshift process.Semantic proximity Read ↗

Q beta RNA bacteriophage: mapping cis-acting elements within an RNA genome.Semantic proximity Read ↗

Structural basis for RNA-genome recognition during bacteriophage Qβ replication.Semantic proximity Read ↗

NMR structure of a classical pseudoknot: interplay of single- and double-stranded RNA.Semantic proximity Read ↗

Selection and characterization of RNAs replicated by Q beta replicase.Semantic proximity Read ↗

Evidence for the Existence of a Pseudoknot Structure at the 3‘ Terminus of the Flavivirus Genomic RNASemantic proximity Read ↗

Structural transition of replicable RNAs during in vitro evolution with Qβ replicase.Semantic proximity Read ↗

Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting.Semantic proximity Read ↗

A loop 2 cytidine-stem 1 minor groove interaction as a positive determinant for pseudoknot-stimulated -1 ribosomal frameshifting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.