Article

Replication of alphaviruses requires a pseudoknot that involves the polyA tail

2022-06-20

Abstract excerpt

<h4>Summary</h4> Alphaviruses, such as Sindbis virus and Chikungunya virus, are RNA viruses with a positive sense single-stranded RNA genome that infect various vertebrates including humans. A conserved sequence element (CSE) of ∼19 nucleotides (nts) in the 3’ non-coding region is important for replication. Despite extensive mutational analysis of the CSE no comprehensive model of this element exists to date. Her...

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Literature Corpus work: 38b8765a-2829-50aa-9057-c1ad2e84312a
DOI: 10.1101/2022.06.20.496828

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